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Rem Sleep Latency Depression. In a sample of 92 inpatients with major depression REM latency showed a unimodal rather than bimodal distribution with peak frequency between 50-59 min on each side of 4. On the basis of these studies we have concluded that with the exception of drug withdrawal states such as CNS depressant or amphetamine withdrawal and narcolepsy shortened REM latency points to a strong affective component in the patients illness. Clinical characteristics associated with sleep onset REM periods Author co-author. The shortening of REM latency in depression typically refers to a change of REM latency from on average 7090 min characterizing healthy sleep to mean values of 5060 min.
The relationship was more marked in male than in female patients. Wave Sleep but also a disinhibition of REM rapid eye movement sleep demonstrated as a shortening of REM latency an increase of REM density as well as total REM sleep time. Studies examining macroarchitecture in depression have predominantly identified changes in REM sleep particularly with depressed individuals exhibiting decreased latency to REM sleep increased. No significant correlation between REM latency and awakening latency. Most of the registered sleep abnormalities in depression also occur in other psychiatric disorders. REM Sleep Latency in Major Depressed Patients Predicts Mood Improvement After Transdermal Nicotine Administration Rafael J.
REM sleep latency.
Shortened REM latency ie the interval between sleep onset and the occurrence of the first REM period increased REM sleep duration and increased REM density ie the frequency of rapid eye movements per REM period have been considered as biological markers of depression which might predict relapse and recurrence. Computer simulations based on the results of phase delay of sleep in normal subjects. A significant inverse relationship appeared between REM latency and awakening latency in depressed patients. Period of time between the onset of sleep and the first REM episode. REM sleep alterations include a decrease in REM sleep latency an increase in REM sleep duration and REM sleep density with respect to depressive episodes. The relationship was more marked in male than in female patients.