2 Deoxyglucose 2 Dg. 16111712 Maher et al 2004 Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Kang and Hwang 2006 2-deoxyglucose. 2-Deoxy-D-Glucose 2-Deoxyglucose is a glucose analog that inhibits glycolysis via its actions on hexokinase the rate limiting step of glycolysis. Therapeutically 2-deoxyglucose is an investigational drug that is being studied as an anticancer and antiviral agent.
2-Deoxyglucose 2-DG a derivative of glucose is able to be phosphorylated by hexokinase resulting in the formation of 2-deoxyglucose-phosphate 2-DG-P 89. 2-Deoxy-D-Glucose 2-Deoxyglucose is a glucose analog that inhibits glycolysis via its actions on hexokinase the rate limiting step of glycolysis. The equipment we have is Agilent HPLCwith UV detector only. Dadurch wird durch kompetitive Hemmung der Abbauweg von Traubenzucker Glucose gehemmt. Inside a cell it is converted to phosphorylated 2-DG 2-DG-P by hexokinase the first and the rate-limiting enzyme in glycolysis. 2-Deoxyglucose 2-DG is best known as an inhibitor of glucose metabolism 1.
2-Deoxy-D-Glucose 2-Deoxyglucose is a glucose analog that inhibits glycolysis via its action on hexokinase the rate limiting step of glycolysis.
However 2-DG-P cannot be metabolized by the second enzyme in glycolysis phosphoglucose isomerase 2. 2-Deoxy-D-Glucose 2-Deoxyglucose is a glucose analog that inhibits glycolysis via its actions on hexokinase the rate limiting step of glycolysis. The equipment we have is Agilent HPLCwith UV detector only. This optical imaging agent has been used for numerous applications including research pertaining to tumor biology tumor metastases diabetes and arthritis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. Therapeutically 2-deoxyglucose is an investigational drug that is being studied as an anticancer and antiviral agent.